Parallel-META is a comprehensive and full-automatic computational toolkit for rapid data mining among metagenomic datasets. Both metagenomic shotgun sequences and 16S/18S rRNA amplicon sequences are accepted. Based on parallel algorithms and optimizations, Parallel-META 3 can achieve a very high speed compare to traditional microbiome analysis pipelines. Now the Parallel-META 3 version 3.4.2 is available at http://bioinfo.single-cell.cn/parallel-meta.html
The following functions have been updated in the new version of Parallel-META 3.
1. Updated the “classification.txt” format to significantly improve the I/O efficiency when the sequencing depth is very large;
2. The 3.4.2 is compatible with both the new format and the old format of “classification.txt”;
3. The 3.4.1 or lower is not compatible with the new format of “classification.txt”;
4. Enabled the “PM-update-taxa” to convert the old format of “classification.txt” to the new format, which can improve the I/O efficiency;
5. Added the un-weighted Meta-Storms distance in “PM-pipeline” and “PM-comp-sam” that ignoring the relative abundance of OTUs.
Thus, we strongly recommend all users to update their Parallel-META 3 to 3.4.2 version.