QSpec-Simu: an open-source framework of virtual microorganism single-cell experimental platform
QSpec-Simu is an open-source framework of virtual microorganism single-cell experimental platform that has main advantages in the following aspects: (1)multiple single-cell phenotypes simulation, including realistic single-cell images, Raman spectra and the effects of in vivo single-cell dynamics (temporal effects, such as the Brownian motion) are simulated, (2)virtual microscope operation interfaces with microscope lens & laser lens movement, focus adjustment, microscope imaging and Raman spectra capture functions, and (3)open development portals for plug-in of different simulation algorithm, single-cell phenotypes, and microscope operations. In addition, as its open source and cross platform design, QSpec-Simu has high portability, compatibility and extensibility; Therefore, QSpec-Simu would be especially useful for evaluation of the phenotype analysis methods on microorganisms.
